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Abstract: Potential Pathogenic Organisms Associated with Neoplasia in Cats: There is increasing evidence suggesting a potential link between infectious organisms and neoplasia in cats. Infectious agents can have a direct role in the development of neoplasia, but can also be shown to predispose to neoplasia through alterations in the immune response or through the creation of a pro-inflammatory environment. Many of these associations have been studied in depth and the agents that have been reported to be associated with neoplasia in cats are summarised in this review.AbstractWe describe the results of a PubMed search (using the following search terms: virology/infectious/feline/leukaemia/neoplasia/) which identified 8 published studies, reporting on the association of feline leukaemia virus (FeLV) with neoplasia in cats. Four of these studies focused on FeLV-associated lymphoma, 2 evaluated the association of FeLV with neoplasia in general and the other 2 focused on FeLV-associated alimentary neoplasia. There are reports of association with FeLV from 8 different countries, including the United Kingdom, Hungary, India, Germany, Greece, Australia, Canada and the United States. Four of the studies have been cited and reviewed by other authors, the other 4 were unreviewed. It is thought that the leukaemic form of FeLV will be found to be the most common form of feline lymphoid neoplasia and the association between FeLV and feline lymphoma remains controversial. Keywords: infectious disease/neoplasia/feline/FeLV/lymphoma.AbstractIn recent years, there has been an increasing focus on the role of infectious diseases in tumour development and progression. Investigations have demonstrated that some infectious organisms can have a direct role in the development of neoplasia, whereas others can predispose to neoplasia by alterations in the immune response, or by creating a pro-inflammatory environment. Feline leukaemia virus (FeLV) is one of the first infectious agents which was recognised as an oncogenic organism, and along with feline immunodeficiency virus (FIV) has received the most attention.
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